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| Saxagliptin |
Saxagliptin is utilized alongside eating routine and practice to lower glucose levels in patients with sort 2 diabetes (condition in which glucose is too high on the grounds that the body does not deliver or utilize insulin typically). Saxagliptin is in a class of meds called dipeptidyl peptidase-4 (DPP-4) inhibitors. It works by expanding the measure of insulin delivered by the body after suppers when glucose is high. Saxagliptin is not used to treat sort 1 diabetes (condition in which the body does not create insulin and, along these lines, can't control the measure of sugar in the blood) or diabetic ketoacidosis (a genuine condition that may create if high glucose is not treated).
After some time, individuals who have diabetes and high glucose can create genuine or life-debilitating confusions, including coronary illness, stroke, kidney issues, nerve harm, and eye issues. Taking medication(s), rolling out way of life improvements (e.g., slim down, work out, stopping smoking), and frequently checking your glucose may deal with your diabetes and enhance your wellbeing. This treatment may likewise diminish your odds of showing at least a bit of kindness assault, stroke, or different diabetes-related intricacies, for example, kidney disappointment, nerve harm (numb, icy legs or feet; diminished sexual capacity in men and ladies), eye issues, including changes or loss of vision, or gum ailment. Your specialist and other social insurance suppliers will converse with you about the most ideal approach to deal with your diabetes.
In what manner ought to this drug be utilized?
Saxagliptin comes as a tablet to take by mouth. It is typically brought once per day with or without sustenance. Take saxagliptin at around similar time each day. Take after the bearings on your medicine mark deliberately, and ask your specialist or drug specialist to clarify any part you don't get it. Take saxagliptin precisely as coordinated. Try not to take pretty much of it or take it more frequently than endorsed by your specialist.
Saxagliptin controls sort 2 diabetes however does not cure it. Keep on taking saxagliptin regardless of the possibility that you feel well. Try not to quit taking saxagliptin without conversing with your specialist.
Your specialist or drug specialist will give you the maker's patient data sheet (Medication Guide) when you start treatment with saxagliptin and every time you refill your remedy. Perused the data deliberately and ask your specialist or drug specialist on the off chance that you have any inquiries. You can likewise visit the Food and Drug Administration (FDA) site (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the producer's site to get the Medication Guide.
Different utilizations for this prescription
This medicine might be endorsed for different uses; approach your specialist or drug specialist for more data.
What exceptional insurances would it be a good idea for me to take after?
Before taking saxagliptin,
tell your specialist and drug specialist in the event that you are susceptible to saxagliptin, whatever other meds, or any of the fixings in saxagliptin tablets. Ask your drug specialist or check the Medication Guide for a rundown of the fixings.
tell your specialist and drug specialist what other remedy and nonprescription solutions, vitamins, healthful supplements, and home grown items you are taking or plan to take. Make sure to specify any of the accompanying: certain antifungal drugs, for example, itraconazole (Onmel, Sporanox) and ketoconazole (Nizoral); clarithromycin (Biaxin); certain prescriptions for HIV (human immunodeficiency infection) or (AIDS, for example, atazanavir (Reyataz, in Evotaz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), and saquinavir (Invirase); insulin or oral meds for diabetes, for example, chlorpropamide (Diabinese), glimepiride (Amaryl, in Duetact), glipizide (Glucotrol), glyburide (Diabeta, Glynase, in Glucovance), nateglinide (Starlix), pioglitazone (Actos, in Actoplus Met, in Duetact), repaglinide (Prandin, in Prandimet), rosiglitazone (Avandia), tolazamide, and tolbutamide; nefazodone; and telithromycin (no more drawn out accessible in the U.S.; Ketek). You specialist may need to change the measurements of your solutions or screen you deliberately for reactions.
tell your specialist in the event that you drink or have ever tipsy a lot of liquor, on the off chance that you have or have ever had pancreatitis (swelling of the pancreas), gallstones, abnormal amounts of triglycerides (greasy substances) in your blood, heart disappointment, diabetic ketoacidosis, or kidney ailment.
tell your specialist in the event that you are pregnant, arrangement to end up pregnant, or are breastfeeding. In the event that you get to be pregnant while taking saxagliptin, call your specialist.
on the off chance that you are having surgery, including dental surgery, tell the specialist or dental specialist that you are taking saxagliptin.
converse with your specialist about what you ought to do in the event that you get hurt or on the off chance that you build up a fever or contamination. These conditions may influence your glucose and the measure of saxagliptin you may require.
What exceptional dietary directions would it be a good idea for me to take after?
Make sure to take after all practice and dietary suggestions made by your specialist or dietitian. It is imperative to eat a solid eating regimen, practice consistently, and shed pounds if fundamental. This will control your diabetes and help saxagliptin work all the more adequately.
What would it be advisable for me to do on the off chance that I overlook a measurement?
Take the missed measurement when you recollect that it. Be that as it may, on the off chance that it is practically time for the following measurement, skirt the missed dosage and proceed with your customary dosing plan. Try not to take a twofold measurement to compensate for a missed one unless your specialist lets you know that you ought to.
What reactions can this pharmaceutical cause?
This solution may bring about changes in your glucose. You ought to know the manifestations of low and high glucose and what to do on the off chance that you have these indications.
Saxagliptin may bring about symptoms. Tell your specialist if any of these side effects are extreme or don't leave:
sore throat
cerebral pain
joint agony
Some symptoms can be not kidding. In the event that you encounter any of these manifestations, quit accepting saxagliptin and call your specialist quickly:
rash
hives
skin peeling
tingling
swelling of the face, lips, tongue or throat
trouble breathing or gulping
raspiness
continuous torment, that starts in the upper left or center of the stomach however may spread to the back
heaving
loss of hunger
over the top tiredness
shortness of breath, particularly when resting
swelling of the feet, lower legs, or legs
sudden weight pick up
Saxagliptin may bring about opposite symptoms. Call your specialist on the off chance that you have any uncommon issues while taking this pharmaceutical.
On the off chance that you encounter a genuine reaction, you or your specialist may send an answer to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program on the web (http://www.fda.gov/Safety/MedWatch) or by telephone (1-800-332-1088).
What would it be a good idea for me to think about capacity and transfer of this drug?
Keep this prescription in the compartment it came in, firmly shut, and out of reach of kids. Store it at room temperature and far from overabundance warmth and dampness (not in the washroom).
Unneeded drugs ought to be discarded in exceptional approaches to guarantee that pets, youngsters, and other individuals can't devour them. In any case, you ought not flush this drug down the can. Rather, the most ideal approach to discard your drug is through a medication reclaim program. Converse with your drug specialist or contact your neighborhood refuse/reusing office to find out about reclaim programs in your group. See the FDA's Safe Disposal of Medicines site (http://goo.gl/c4Rm4p) for more data on the off chance that you don't have admittance to a reclaim program.
If there should be an occurrence of crisis/overdose
If there should be an occurrence of overdose, call your nearby toxin control focus at 1-800-222-1222. In the event that the casualty has caved in or is not breathing, call neighborhood crisis administrations at 911.
What other data would it be a good idea for me to know?
Keep all meetings with your specialist and the lab. Your specialist will most likely request certain research facility tests before and amid your treatment with saxagliptin to check your body's reaction to it. Your glucose and glycosylated hemoglobin (HbA1c) ought to be checked frequently to decide your reaction to saxagliptin. Your specialist may likewise let you know how to check your reaction to saxagliptin by measuring your blood or pee sugar levels at home. Take after these bearings painstakingly.
You ought to dependably wear a diabetic ID arm jewelery to make certain you get legitimate treatment in a crisis.
Try not to let any other person take your prescription. Ask your drug specialist any inquiries you have about refilling your medicine.
It is imperative for you to keep a composed rundown of the greater part of the solution and nonprescription (over-the-counter) drugs you are taking, and in addition any items, for example, vitamins, minerals, or other dietary supplements. You ought to carry this rundown with you every time you visit a specialist or on the off chance that you are admitted to a doctor's facility. It is likewise critical data to convey with you if there should arise an occurrence of crises.
Mark namesDo NOT utilize saxagliptin if:
you are sensitive to any fixing in saxagliptin
you have sort 1 diabetes
you have high blood or pee ketone levels connected with diabetes (diabetic ketoacidosis)
Contact your specialist or human services supplier immediately if any of these apply to you.
Commercial
Slideshow
Invokana Insights: 10 Drug-Specific Facts You Should Know
Before utilizing saxagliptin:
Some therapeutic conditions may communicate with saxagliptin. Tell your specialist or drug specialist in the event that you have any medicinal conditions, particularly if any of the accompanying apply to you:
on the off chance that you are pregnant, wanting to wind up pregnant, or are bosom bolstering
on the off chance that you are taking any solution or nonprescription drug, home grown arrangement, or dietary supplement
on the off chance that you have hypersensitivities to pharmaceuticals, sustenances, or different substances
on the off chance that you have a background marked by angioedema (swelling of the hands, confront, lips, eyes, throat, or tongue; trouble gulping or breathing; or dryness) brought about by another DPP-4 in
After some time, individuals who have diabetes and high glucose can create genuine or life-debilitating confusions, including coronary illness, stroke, kidney issues, nerve harm, and eye issues. Taking medication(s), rolling out way of life improvements (e.g., slim down, work out, stopping smoking), and frequently checking your glucose may deal with your diabetes and enhance your wellbeing. This treatment may likewise diminish your odds of showing at least a bit of kindness assault, stroke, or different diabetes-related intricacies, for example, kidney disappointment, nerve harm (numb, icy legs or feet; diminished sexual capacity in men and ladies), eye issues, including changes or loss of vision, or gum ailment. Your specialist and other social insurance suppliers will converse with you about the most ideal approach to deal with your diabetes.
In what manner ought to this drug be utilized?
Saxagliptin comes as a tablet to take by mouth. It is typically brought once per day with or without sustenance. Take saxagliptin at around similar time each day. Take after the bearings on your medicine mark deliberately, and ask your specialist or drug specialist to clarify any part you don't get it. Take saxagliptin precisely as coordinated. Try not to take pretty much of it or take it more frequently than endorsed by your specialist.
Saxagliptin controls sort 2 diabetes however does not cure it. Keep on taking saxagliptin regardless of the possibility that you feel well. Try not to quit taking saxagliptin without conversing with your specialist.
Your specialist or drug specialist will give you the maker's patient data sheet (Medication Guide) when you start treatment with saxagliptin and every time you refill your remedy. Perused the data deliberately and ask your specialist or drug specialist on the off chance that you have any inquiries. You can likewise visit the Food and Drug Administration (FDA) site (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the producer's site to get the Medication Guide.
Different utilizations for this prescription
This medicine might be endorsed for different uses; approach your specialist or drug specialist for more data.
What exceptional insurances would it be a good idea for me to take after?
Before taking saxagliptin,
tell your specialist and drug specialist in the event that you are susceptible to saxagliptin, whatever other meds, or any of the fixings in saxagliptin tablets. Ask your drug specialist or check the Medication Guide for a rundown of the fixings.
tell your specialist and drug specialist what other remedy and nonprescription solutions, vitamins, healthful supplements, and home grown items you are taking or plan to take. Make sure to specify any of the accompanying: certain antifungal drugs, for example, itraconazole (Onmel, Sporanox) and ketoconazole (Nizoral); clarithromycin (Biaxin); certain prescriptions for HIV (human immunodeficiency infection) or (AIDS, for example, atazanavir (Reyataz, in Evotaz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), and saquinavir (Invirase); insulin or oral meds for diabetes, for example, chlorpropamide (Diabinese), glimepiride (Amaryl, in Duetact), glipizide (Glucotrol), glyburide (Diabeta, Glynase, in Glucovance), nateglinide (Starlix), pioglitazone (Actos, in Actoplus Met, in Duetact), repaglinide (Prandin, in Prandimet), rosiglitazone (Avandia), tolazamide, and tolbutamide; nefazodone; and telithromycin (no more drawn out accessible in the U.S.; Ketek). You specialist may need to change the measurements of your solutions or screen you deliberately for reactions.
tell your specialist in the event that you drink or have ever tipsy a lot of liquor, on the off chance that you have or have ever had pancreatitis (swelling of the pancreas), gallstones, abnormal amounts of triglycerides (greasy substances) in your blood, heart disappointment, diabetic ketoacidosis, or kidney ailment.
tell your specialist in the event that you are pregnant, arrangement to end up pregnant, or are breastfeeding. In the event that you get to be pregnant while taking saxagliptin, call your specialist.
on the off chance that you are having surgery, including dental surgery, tell the specialist or dental specialist that you are taking saxagliptin.
converse with your specialist about what you ought to do in the event that you get hurt or on the off chance that you build up a fever or contamination. These conditions may influence your glucose and the measure of saxagliptin you may require.
What exceptional dietary directions would it be a good idea for me to take after?
Make sure to take after all practice and dietary suggestions made by your specialist or dietitian. It is imperative to eat a solid eating regimen, practice consistently, and shed pounds if fundamental. This will control your diabetes and help saxagliptin work all the more adequately.
What would it be advisable for me to do on the off chance that I overlook a measurement?
Take the missed measurement when you recollect that it. Be that as it may, on the off chance that it is practically time for the following measurement, skirt the missed dosage and proceed with your customary dosing plan. Try not to take a twofold measurement to compensate for a missed one unless your specialist lets you know that you ought to.
What reactions can this pharmaceutical cause?
This solution may bring about changes in your glucose. You ought to know the manifestations of low and high glucose and what to do on the off chance that you have these indications.
Saxagliptin may bring about symptoms. Tell your specialist if any of these side effects are extreme or don't leave:
sore throat
cerebral pain
joint agony
Some symptoms can be not kidding. In the event that you encounter any of these manifestations, quit accepting saxagliptin and call your specialist quickly:
rash
hives
skin peeling
tingling
swelling of the face, lips, tongue or throat
trouble breathing or gulping
raspiness
continuous torment, that starts in the upper left or center of the stomach however may spread to the back
heaving
loss of hunger
over the top tiredness
shortness of breath, particularly when resting
swelling of the feet, lower legs, or legs
sudden weight pick up
Saxagliptin may bring about opposite symptoms. Call your specialist on the off chance that you have any uncommon issues while taking this pharmaceutical.
On the off chance that you encounter a genuine reaction, you or your specialist may send an answer to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program on the web (http://www.fda.gov/Safety/MedWatch) or by telephone (1-800-332-1088).
What would it be a good idea for me to think about capacity and transfer of this drug?
Keep this prescription in the compartment it came in, firmly shut, and out of reach of kids. Store it at room temperature and far from overabundance warmth and dampness (not in the washroom).
Unneeded drugs ought to be discarded in exceptional approaches to guarantee that pets, youngsters, and other individuals can't devour them. In any case, you ought not flush this drug down the can. Rather, the most ideal approach to discard your drug is through a medication reclaim program. Converse with your drug specialist or contact your neighborhood refuse/reusing office to find out about reclaim programs in your group. See the FDA's Safe Disposal of Medicines site (http://goo.gl/c4Rm4p) for more data on the off chance that you don't have admittance to a reclaim program.
If there should be an occurrence of crisis/overdose
If there should be an occurrence of overdose, call your nearby toxin control focus at 1-800-222-1222. In the event that the casualty has caved in or is not breathing, call neighborhood crisis administrations at 911.
What other data would it be a good idea for me to know?
Keep all meetings with your specialist and the lab. Your specialist will most likely request certain research facility tests before and amid your treatment with saxagliptin to check your body's reaction to it. Your glucose and glycosylated hemoglobin (HbA1c) ought to be checked frequently to decide your reaction to saxagliptin. Your specialist may likewise let you know how to check your reaction to saxagliptin by measuring your blood or pee sugar levels at home. Take after these bearings painstakingly.
You ought to dependably wear a diabetic ID arm jewelery to make certain you get legitimate treatment in a crisis.
Try not to let any other person take your prescription. Ask your drug specialist any inquiries you have about refilling your medicine.
It is imperative for you to keep a composed rundown of the greater part of the solution and nonprescription (over-the-counter) drugs you are taking, and in addition any items, for example, vitamins, minerals, or other dietary supplements. You ought to carry this rundown with you every time you visit a specialist or on the off chance that you are admitted to a doctor's facility. It is likewise critical data to convey with you if there should arise an occurrence of crises.
Mark namesDo NOT utilize saxagliptin if:
you are sensitive to any fixing in saxagliptin
you have sort 1 diabetes
you have high blood or pee ketone levels connected with diabetes (diabetic ketoacidosis)
Contact your specialist or human services supplier immediately if any of these apply to you.
Commercial
Slideshow
Invokana Insights: 10 Drug-Specific Facts You Should Know
Before utilizing saxagliptin:
Some therapeutic conditions may communicate with saxagliptin. Tell your specialist or drug specialist in the event that you have any medicinal conditions, particularly if any of the accompanying apply to you:
on the off chance that you are pregnant, wanting to wind up pregnant, or are bosom bolstering
on the off chance that you are taking any solution or nonprescription drug, home grown arrangement, or dietary supplement
on the off chance that you have hypersensitivities to pharmaceuticals, sustenances, or different substances
on the off chance that you have a background marked by angioedema (swelling of the hands, confront, lips, eyes, throat, or tongue; trouble gulping or breathing; or dryness) brought about by another DPP-4 in
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